Follow-The-Filings

Featured 13F manager

Avidity Partners Management LP David Witzke

Dallas, TX 21 processed 13Fs on this site · 2021 Q3–2026 Q2

  • $624M
  • 45 Positions
  • 2026 Q2
  • +41.2% QoQ
  • Top 5 70.9%

David Witzke files Avidity Partners Management LP as a Form 13F. The latest book is 2026 Q2 at $624M, up 41.2% QoQ, led by Dianthus Therapeutics, Cg Oncology, and Oruka Therapeutics.

Portfolio

2026 Q2 · filed 8/14/2026 · 45 long · top 12 shown

top 5 70.9% · top 10 81.9%

AUM over time

2026 Q2 $624M +41.2% QoQ
2021 Q3 · $4.5B 2021 Q3 · $4.5B
Q3 2021
2021 Q4 · $4.7B · +4.5% QoQ 2021 Q4 · $4.7B · +4.5% QoQ
Q4
2022 Q1 · $4.8B · +1.9% QoQ 2022 Q1 · $4.8B · +1.9% QoQ
Q1 2022
2022 Q2 · $4.4B · −9.3% QoQ 2022 Q2 · $4.4B · −9.3% QoQ
Q2
2022 Q3 · $4.9B · +12.9% QoQ 2022 Q3 · $4.9B · +12.9% QoQ
Q3
2022 Q4 · $4.6B · −6.2% QoQ 2022 Q4 · $4.6B · −6.2% QoQ
Q4
2023 Q1 · $3B · −34.7% QoQ 2023 Q1 · $3B · −34.7% QoQ
Q1 2023
2023 Q2 · $2.9B · −5.0% QoQ 2023 Q2 · $2.9B · −5.0% QoQ
Q2
2023 Q3 · $2.5B · −13.3% QoQ 2023 Q3 · $2.5B · −13.3% QoQ
Q3
2023 Q4 · $2.7B · +10.5% QoQ 2023 Q4 · $2.7B · +10.5% QoQ
Q4
2024 Q1 · $3.1B · +13.0% QoQ 2024 Q1 · $3.1B · +13.0% QoQ
Q1 2024
2024 Q2 · $2.4B · −24.1% QoQ 2024 Q2 · $2.4B · −24.1% QoQ
Q2
2024 Q3 · $2B · −16.7% QoQ 2024 Q3 · $2B · −16.7% QoQ
Q3
2024 Q4 · $1B · −48.1% QoQ 2024 Q4 · $1B · −48.1% QoQ
Q4
2025 Q1 · $525M · −48.4% QoQ 2025 Q1 · $525M · −48.4% QoQ
Q1 2025
2025 Q2 · $502M · −4.4% QoQ 2025 Q2 · $502M · −4.4% QoQ
Q2
2025 Q3 · $439M · −12.5% QoQ 2025 Q3 · $439M · −12.5% QoQ
Q3
2025 Q4 · $347M · −21.0% QoQ 2025 Q4 · $347M · −21.0% QoQ
Q4
2026 Q1 · $442M · +27.4% QoQ 2026 Q1 · $442M · +27.4% QoQ
Q1 2026
2026 Q2 · $624M · +41.2% QoQ 2026 Q2 · $624M · +41.2% QoQ
Q2

Book

2024 Q1 2023 Q4 · filed 15 May · long equity

Fusion Pharmaceuticals 4.47% Hold 6,500,328 $21.32 $139M
BSX - Boston Scientific 4.32% Add +3.5% 1,956,000 $68.49 $134M +66,000 +$25M
ARVN - Arvinas 3.97% Add 0.0% 2,985,190 $41.28 $123M +73 +$361K
ISRG - Intuitive Surgical 2.91% Add +165.9% 226,000 $399.09 $90M +141,000 +$62M
DNTH - Dianthus Therapeutics 2.63% Add +123.2% 2,717,554 $30.00 $82M +1,500,000 +$69M
ACHC — 2.57% Reduce −13.1% 1,005,000 $79.22 $80M −151,692 −$10M
NBIX - Neurocrine Biosciences 2.39% Reduce −18.5% 536,500 $137.92 $74M −121,500 −$13M
NTRA - Natera 2.37% Reduce −27.6% 803,300 $91.46 $73M −306,700 +$4M
JAZZ - Jazz Pharmaceuticals 2.27% Add +19.4% 584,000 $120.42 $70M +94,881 +$10M
AVTR - Avantor 2.22% Add +27.0% 2,695,000 $25.57 $69M +573,156 +$20M
CI - The Cigna Group 2.16% New 184,500 $363.19 $67M +184,500 +$67M
MRK - Merck & 2.14% New 502,000 $131.95 $66M +502,000 +$66M
REGN - Regeneron Pharmaceuticals 2.11% Hold 68,000 $962.49 $65M
CGON - Cg Oncology 2.06% New 1,454,765 $43.90 $64M +1,454,765 +$64M
ILMN - Illumina 2.05% New 464,100 $137.32 $64M +464,100 +$64M
THC - Tenet Healthcare 2.04% Reduce −31.0% 601,000 $105.11 $63M −270,000 −$3M
ALGN - Align Technology 2.00% Add +21.3% 189,000 $327.92 $62M +33,200 +$19M
SNDX - Syndax Pharmaceuticals 1.85% Reduce −38.9% 2,412,500 $23.80 $57M −1,537,500 −$28M
LLY - Eli Lilly & 1.76% Reduce −17.6% 70,000 $777.96 $54M −15,000 +$5M
UTHR - United Therapeutics 1.61% Reduce −8.5% 217,000 $229.72 $50M −20,202 −$2M
Alpine Immune Sciences 1.50% New 1,174,700 $39.64 $47M +1,174,700 +$47M
RARE — 1.41% Add +10.5% 933,500 $46.69 $44M +89,000 +$3M
CVS - Cvs Health 1.40% Reduce −26.4% 545,000 $79.76 $43M −195,000 −$15M
SGRY - Surgery Partners 1.39% Add +23.9% 1,445,000 $29.83 $43M +279,068 +$6M
Intra-Cellular Therapies 1.34% Reduce −15.5% 600,000 $69.20 $42M −110,000 −$9M
ABBV - Abbvie 1.33% Reduce −20.2% 227,000 $182.10 $41M −57,405 −$3M
Blueprint Medicines 1.30% Reduce −30.7% 426,000 $94.86 $40M −189,000 −$16M
Legend Biotech 1.21% Reduce −2.4% 668,300 $56.09 $37M −16,700 −$4M
GPCR - Structure Therapeutics 1.19% Reduce −20.0% 864,000 $42.86 $37M −216,000 −$7M
ALNY - Alnylam Pharmaceuticals 1.17% New 243,000 $149.45 $36M +243,000 +$36M
DHR - Danaher 1.16% Reduce −50.4% 143,800 $249.72 $36M −146,200 −$31M
IDYA - Ideaya Biosciences 1.13% Reduce −47.4% 799,700 $43.88 $35M −720,300 −$19M
AXSM - Axsome Therapeutics 1.11% Reduce −6.2% 431,000 $79.80 $34M −28,400 −$2M
XENE - Xenon Pharmaceuticals 0.99% Reduce −13.0% 710,000 $43.05 $31M −105,993 −$7M
LNTH - Lantheus 0.96% Add +26.3% 480,000 $62.24 $30M +100,000 +$6M
CRBU - Caribou Biosciences 0.96% Reduce −9.0% 5,785,352 $5.14 $30M −574,860 −$7M
MIRM - Mirum Pharmaceuticals 0.93% Hold 1,142,850 $25.12 $29M
RCKT - Rocket Pharmaceuticals 0.89% Reduce −40.4% 1,025,000 $26.94 $28M −694,103 −$24M
Regenxbio 0.88% New 1,300,064 $21.07 $27M +1,300,064 +$27M
APGE - Apogee Therapeutics 0.82% New 384,893 $66.45 $26M +384,893 +$26M
NMRA - Neumora Therapeutics 0.80% Reduce −9.6% 1,800,000 $13.75 $25M −190,632 −$9M
DXCM - Dexcom 0.79% New 176,900 $138.70 $25M +176,900 +$25M
NGNE - Neurogene 0.76% Reduce −0.2% 465,237 $50.90 $24M −1,006 +$15M
Jasper Therapeutics 0.72% New 760,000 $29.36 $22M +760,000 +$22M
Immunome 0.70% Reduce −34.5% 873,891 $24.68 $22M −459,588 +$7M
TMO - Thermo Fisher Scientific 0.69% Reduce −80.0% 36,600 $581.21 $21M −146,000 −$76M
GKOS - Glaukos 0.68% New 224,000 $94.29 $21M +224,000 +$21M
RVMD - Revolution Medicines 0.66% Add +958.3% 635,000 $32.23 $20M +575,000 +$19M
PCVX - Vaxcyte 0.63% Reduce −50.2% 284,000 $68.31 $19M −286,137 −$16M
Immunocore 0.60% Reduce −4.6% 286,400 $65.00 $19M −13,800 −$2M

Showing top 50 of 85 by value

Exits / last held

not current holdings · last reported size, unchanged · gone vs 2023 Q4

Stock % of portfolio Recent activity Shares Reported price* Value Share change $ change
Karuna Therapeutics 2.38% Exit 0 $316.51 $65M −206,000 −$65M
Immunogen 1.98% Exit 0 $29.65 $54M −1,829,215 −$54M
ZTS - Zoetis · CL A 1.73% Exit 0 $197.37 $47M −240,000 −$47M
HUM - Humana 1.67% Exit 0 $457.81 $46M −100,000 −$46M
BDX - Becton Dickinson & 1.47% Exit 0 $243.83 $40M −165,706 −$40M
UNH - Unitedhealth Group 1.12% Exit 0 $526.46 $31M −58,500 −$31M
ARWR - Arrowhead Pharmaceuticals 0.80% Exit 0 $30.60 $22M −714,000 −$22M
CRNX — 0.69% Exit 0 $35.58 $19M −529,000 −$19M
Verona Pharma 0.57% Exit 0 $19.88 $16M −780,900 −$16M
A - Agilent Technologies 0.50% Exit 0 $139.03 $14M −99,000 −$14M
INTC - Intellia Therapeutics 0.50% Exit 0 $30.49 $14M −447,434 −$14M
ARGX - Argenx Se 0.43% Exit 0 $380.42 $12M −31,000 −$12M
Holding 0.43% Exit 0 $42.40 $12M −276,888 −$12M
TVTX - Travere Therapeutics 0.27% Exit 0 $8.99 $7M −827,010 −$7M
Akero Therapeutics 0.20% Exit 0 $23.35 $5M −235,000 −$5M
CMPX - Compass Therapeutics 0.09% Exit 0 $1.56 $2M −1,599,600 −$2M
AMLX - Amylyx Pharmaceuticals 0.03% Exit 0 $14.71 $949K −64,501 −$949K
Caremax · CL A 0.01% Exit 0 $0.4984 $317K −636,000 −$317K

* Reported price is value ÷ shares from the 13F as of period end — not a live market quote. Weight % is each long-equity position ÷ full 13F AUM, so rows may not sum to 100% when the filing includes options or other non-equity (excluded from this table). Share change and $ change are vs 2023 Q4. Click column headers to sort · click New / Hold / Add / Reduce to promote that move type to the top. Exit opens the last-held block below.

Filings history

20 periods · normalized AUM · open a period for holdings

Period Holdings AUM QoQ Form Filed Filing ID
2026 Q2 45 $624M +41.2% 13F-HR 8/14/2026 000179182726000005
2026 Q1 45 $494M new holds 5/28/2026 000179182726000004
2026 Q1 46 $442M +27.4% 13F-HR 5/13/2026 000179182726000003
2025 Q4 39 $347M −21.0% 13F-HR 2/13/2026 000179182726000002
2025 Q3 43 $439M −12.5% 13F-HR 11/14/2025 000179182725000008
2025 Q2 56 $502M −4.4% 13F-HR 8/14/2025 000179182725000007
2025 Q1 67 $525M −48.4% 13F-HR 5/15/2025 000179182725000005
2024 Q4 63 $1B −48.1% 13F-HR 2/14/2025 000179182725000002
2024 Q3 81 $2B −16.7% 13F-HR 11/14/2024 000179182724000011
2024 Q2 85 $2.4B −24.1% 13F-HR 8/14/2024 000179182724000007
2024 Q1 90 $3.1B +13.0% 13F-HR 5/15/2024 000179182724000004
2023 Q4 74 $2.7B +10.5% 13F-HR 2/14/2024 000179182724000002
2023 Q3 83 $2.5B −13.3% 13F-HR 11/14/2023 000179182723000006
2023 Q2 93 $2.9B −5.0% 13F-HR 8/14/2023 000179182723000004
2023 Q1 83 $3B −34.7% 13F-HR 5/15/2023 000179182723000003
2022 Q4 85 $4.6B −6.2% 13F-HR 2/14/2023 000179182723000002
2022 Q3 97 $4.9B +12.9% 13F-HR 11/14/2022 000179182722000008
2022 Q2 82 $4.4B −9.3% 13F-HR 8/15/2022 000179182722000006
2022 Q1 92 $4.8B +1.9% 13F-HR 5/16/2022 000179182722000004
2021 Q4 97 $4.7B +4.5% 13F-HR 2/14/2022 000179182722000002
2021 Q3 105 $4.5B 13F-HR 11/15/2021 000179182721000006

About

Avidity Partners Management LP

21 processed 13Fs on this site · 2021 Q3–2026 Q2

Entity
Avidity Partners Management LP
Notable person
David Witzke
Location
Dallas, TX
All SEC filings
View on sec.gov