Follow-The-Filings

Security

IONS

Ionis Pharmaceuticals Inc. · COM

Equity holders as of 2026 Q1 (each manager’s latest book)

18 owners 2 exits max 13.6% (Tweedy, Browne Co. LLC)

grid → activity →
owners 18
max % 13.6%
tracked value $2B
qoq A 9 R 8 E 2

holders

sorted by % of portfolio · long equity only · exits show last held size

manager % port activity shares value history
Tweedy, Browne Co. LLC 2026 Q1 13.6% Reduce -7.7% 2,275,625 $171M hist
Two Sigma Investments, LP 2025 Q4 stale 0.3% Add +68.7% 2,658,646 $210M hist
Cathie Wood - Ark Investment Management LLC 2026 Q1 0.2% Reduce -31.7% 288,716 $22M hist
Renaissance Technologies LLC 2026 Q1 0.0% Add +36.6% 305,549 $23M hist
Israel Englander - Millennium Management LLC 2026 Q1 0.0% Add +1027.5% 1,051,506 $79M hist
Vanguard Group Inc. 2025 Q4 stale 0.0% Reduce -0.3% 16,440,459 $1.3B hist
D. E. Shaw & Co., Inc. 2026 Q1 0.0% Add +29.1% 429,599 $32M hist
Joel Greenblatt - Gotham Asset Management, LLC 2026 Q1 0.0% Add +129.0% 98,968 $7M hist
Ken Griffin - Citadel Advisors LLC 2026 Q1 0.0% Reduce -55.8% 942,534 $71M hist
Marshall Wace - Marshall Wace, LLP 2026 Q1 0.0% Reduce -62.7% 95,954 $7M hist
Ron Baron - Bamco Inc. /NY/ (Baron Capital) 2026 Q1 0.0% Add +25.0% 45,000 $3M hist
Murray Stahl - Horizon Kinetics Asset Management LLC 2026 Q1 0.0% Reduce -4.4% 11,428 $858 hist
Norges Bank 2025 Q4 stale 0.0% Reduce -28.9% 320,160 $25M hist
Ken Fisher - Fisher Asset Management, LLC 2026 Q1 0.0% Reduce -0.1% 141,544 $11M hist
Cliff Asness - Aqr Capital Management LLC 2026 Q1 0.0% Add +53.4% 28,783 $2M hist
Natixis Advisors, LLC 2026 Q1 0.0% Add +8.4% 23,721 $2M hist
Farallon Capital Management LLC 2026 Q1 0.0% — 4,800 $360 hist
Ancora Advisors LLC 2026 Q1 0.0% Add +2.1% 2,391 $180 hist
Ray Dalio - Bridgewater Associates, LP exited 2026 Q1 last 2025 Q4 0.0% Exit -0.02 pp 67,706 $5M hist
Dmitry Balyasny - Balyasny Asset Management L.P. exited 2026 Q1 last 2025 Q4 0.0% Exit -0.01 pp 120,577 $10M hist

18 current · 2 exited last period · options excluded

financials

US-GAAP annual · as tagged in Form 10-K · fiscal years · values link to the SEC filing

Income statement

Metric FY2023 FY2024 FY2025
Revenue $787.65M $705.14M $943.71M
Gross profit * $778.51M $693.92M $927.8M
Gross margin * 98.8% 98.4% 98.3%
Net income -$366.29M -$453.9M -$381.39M
Net margin * -46.5% -64.4% -40.4%

Balance sheet

Metric FY2023 FY2024 FY2025
Total current assets $2.64B $2.62B $2.99B
Total non-current assets * $348.22M $383.38M $533.2M
Total assets $2.99B $3B $3.52B
Total current liabilities $448.09M $309.32M $781.57M
Total non-current liabilities * $2.16B $2.11B $2.25B
Total equity $386.69M $588.35M $489.09M

Cash flow

Metric FY2023 FY2024 FY2025
Cash from operations -$307.51M -$500.95M -$268.58M
Cash from investing -$214.13M -$134.03M -$277.78M
Cash from financing $644.08M $478.06M $675.84M
Net change in cash $122.79M -$157.19M $130.18M

Source: SEC companyfacts (US-GAAP 10-K) · * = computed (not a single XBRL tag) · fiscal year as labeled by the issuer · not adjusted or audited by Follow-The-Filings

ownership over time

filing count by report period · click a bar for that quarter’s holders