Follow-The-Filings

Featured 13F manager

DAFNA Capital Management LLC Nathan Fischel

Los Angeles, CA 20 processed 13Fs on this site · 2021 Q3–2026 Q2

  • $524M
  • 88 Positions
  • 2026 Q2
  • +19.1% QoQ
  • Top 5 40.2%

Nathan Fischel files DAFNA Capital Management LLC as a Form 13F. The latest book is 2026 Q2 at $524M, up 19.1% QoQ, led by Revolution Medicines, Spdr S&P Biotech ETF, and Compass Pathways.

Portfolio

2026 Q2 · filed 8/14/2026 · 88 long · top 12 shown

top 5 40.2% · top 10 56.2%

AUM over time

2026 Q2 $524M +19.1% QoQ
2021 Q3 · $377M 2021 Q3 · $377M
Q3 2021
2021 Q4 · $398M · +5.6% QoQ 2021 Q4 · $398M · +5.6% QoQ
Q4
2022 Q1 · $384M · −3.5% QoQ 2022 Q1 · $384M · −3.5% QoQ
Q1 2022
2022 Q2 · $367M · −4.4% QoQ 2022 Q2 · $367M · −4.4% QoQ
Q2
2022 Q3 · $372M · +1.4% QoQ 2022 Q3 · $372M · +1.4% QoQ
Q3
2022 Q4 · $355M · −4.6% QoQ 2022 Q4 · $355M · −4.6% QoQ
Q4
2023 Q1 · $334M · −5.9% QoQ 2023 Q1 · $334M · −5.9% QoQ
Q1 2023
2023 Q2 · $366M · +9.6% QoQ 2023 Q2 · $366M · +9.6% QoQ
Q2
2023 Q3 · $321M · −12.3% QoQ 2023 Q3 · $321M · −12.3% QoQ
Q3
2023 Q4 · $417M · +29.9% QoQ 2023 Q4 · $417M · +29.9% QoQ
Q4
2024 Q1 · $439M · +5.3% QoQ 2024 Q1 · $439M · +5.3% QoQ
Q1 2024
2024 Q2 · $419M · −4.6% QoQ 2024 Q2 · $419M · −4.6% QoQ
Q2
2024 Q3 · $423M · +1.0% QoQ 2024 Q3 · $423M · +1.0% QoQ
Q3
2024 Q4 · $393M · −7.1% QoQ 2024 Q4 · $393M · −7.1% QoQ
Q4
2025 Q1 · $353M · −10.2% QoQ 2025 Q1 · $353M · −10.2% QoQ
Q1 2025
2025 Q2 · $362M · +2.5% QoQ 2025 Q2 · $362M · +2.5% QoQ
Q2
2025 Q3 · $405M · +11.9% QoQ 2025 Q3 · $405M · +11.9% QoQ
Q3
2025 Q4 · $431M · +6.4% QoQ 2025 Q4 · $431M · +6.4% QoQ
Q4
2026 Q1 · $440M · +2.1% QoQ 2026 Q1 · $440M · +2.1% QoQ
Q1 2026
2026 Q2 · $524M · +19.1% QoQ 2026 Q2 · $524M · +19.1% QoQ
Q2

Book

2026 Q1 2025 Q4 · filed 15 May · long equity

RVMD - Revolution Medicines 12.85% Reduce −3.9% 580,678 $97.25 $56M −23,836 +$8M
XBI - Spdr S&P Biotech ETF 9.25% Reduce −5.3% 318,505 $127.73 $41M −18,000 −$347K
STXS - Stereotaxis 5.73% Hold 13,680,554 $1.84 $25M
DAWNGBX — 4.77% Reduce −2.1% 978,463 $21.44 $21M −20,700 +$12M
ATRC - Atricure 3.88% Hold 597,431 $28.53 $17M
IDYA - Ideaya Biosciences 3.61% Reduce −5.9% 476,740 $33.32 $16M −30,000 −$2M
XENE - Xenon Pharmaceuticals 3.32% Reduce −12.9% 250,772 $58.15 $15M −37,167 +$2M
CYTK - Cytokinetics 3.26% Reduce −41.4% 217,497 $65.91 $14M −153,500 −$9M
CMPS - Compass Pathways 3.04% Add +198.2% 2,418,882 $5.53 $13M +1,607,836 +$8M
NKTR - Nektar Therapeutics 2.70% Add +120.2% 165,178 $71.95 $12M +90,180 +$9M
NDAQ - Ishares Nasdaq Biotech Indx 2.39% Reduce −8.8% 62,095 $168.85 $10M −6,000 −$1M
RCUS - Arcus Biosciences 2.18% Add +2.9% 443,829 $21.60 $10M +12,500 −$692K
NBIX - Neurocrine Biosciences 2.12% Hold 70,615 $131.74 $9M
LRMR - Larimar Therapeutics 2.08% Add +116.1% 2,029,164 $4.50 $9M +1,090,000 +$6M
BCAX - Bicara Therapeutics 1.91% Add +61.2% 421,733 $19.89 $8M +160,150 +$4M
AXGN - Axogen 1.88% Reduce −47.6% 249,960 $33.13 $8M −226,866 −$7M
BHVN - Biohaven 1.63% Reduce −11.5% 845,735 $8.46 $7M −109,500 −$4M
TNDM - Tandem Diabetes Care 1.55% Hold 355,208 $19.17 $7M
DNLI - Denali Therapeutics 1.39% Hold 318,500 $19.20 $6M
IPSC - Century Therapeutics 1.25% Reduce −12.9% 2,434,353 $2.26 $6M −359,233 +$3M
DXCM - Dexcom 1.23% Reduce −2.3% 86,279 $62.80 $5M −2,000 −$441K
Kalvista Pharmaceuticals 1.22% Reduce −25.1% 267,402 $20.13 $5M −89,400 −$380K
ASND - Ascendis Pharma A/S 1.21% Reduce −17.7% 23,177 $228.73 $5M −5,000 −$707K
MBX - Mbx Biosciences 1.19% Add +6.2% 175,465 $29.85 $5M +10,200 +$25K
INGN - Inogen 1.19% Add +2.2% 845,179 $6.18 $5M +18,108 −$335K
SNDX - Syndax Pharmaceuticals 1.16% Reduce −21.8% 217,355 $23.36 $5M −60,500 −$760K
ALKS - Alkermes 1.12% Add +7.1% 139,482 $35.36 $5M +9,234 +$1M
STOK - Stoke Therapeutics 0.97% Add +20.2% 130,875 $32.56 $4M +22,000 +$806K
BCRX - Biocryst Pharmaceuticals 0.93% Add +2.9% 430,248 $9.52 $4M +11,993 +$834K
LKFT - Galapagos 0.89% Hold 130,175 $30.00 $4M
IMVT - Immunovant 0.85% Hold 150,524 $24.84 $4M
EWTX - Edgewise Therapeutics 0.80% Reduce −29.7% 112,236 $31.50 $4M −47,500 −$428K
MPLT - Maplight Therapeutics 0.79% Add +18.9% 171,006 $20.33 $3M +27,242 +$951K
ALLO - Allogene Therapeutics 0.76% Reduce −0.7% 1,370,118 $2.44 $3M −10,000 +$1M
PRCT - Procept Biorobotics 0.68% Hold 120,000 $25.01 $3M
ALGN - Align Technology 0.58% Reduce −6.3% 15,000 $171.43 $3M −1,000 +$73K
PRQR - Proqr Therapeutics 0.58% Hold 1,567,561 $1.62 $3M
CYBN - Cybin 0.54% Add +9.5% 498,361 $4.80 $2M +43,343 −$1M
RAPP - Rapport Therapeutics 0.53% Hold 75,000 $31.29 $2M
PODD - Insulet 0.52% Add +58.2% 10,870 $209.84 $2M +4,000 +$328K
GPCR - Structure Therapeutics 0.51% Add +25.7% 46,500 $48.20 $2M +9,500 −$332K
Immatics 0.51% Reduce −13.5% 225,860 $9.84 $2M −35,278 −$519K
CLDX - Celldex Therapeutics 0.49% Hold 68,518 $31.72 $2M
LXEO - Lexeo Therapeutics 0.49% Add +10.6% 377,059 $5.74 $2M +36,200 −$1M
ALEC - Alector 0.44% Hold 908,351 $2.15 $2M
VKTX - Viking Therapeutics 0.44% Hold 59,516 $32.54 $2M
KURA - Kura Oncology 0.44% Hold 235,868 $8.13 $2M
PROF - Profound Medical 0.39% Reduce −7.9% 263,005 $6.48 $2M −22,705 −$544K
FULC - Fulcrum Therapeutics 0.36% New 205,000 $7.67 $2M +205,000 +$2M
AQST - Aquestive Therapeutics 0.35% Reduce −2.0% 368,415 $4.15 $2M −7,500 −$899K

Showing top 50 of 82 by value

Exits / last held

not current holdings · last reported size, unchanged · gone vs 2025 Q4

Stock % of portfolio Recent activity Shares Reported price* Value Share change $ change
CATBUSD - Astria Therapeutics 0.93% Exit 0 $13.09 $4M −304,775 −$4M
ERAS - Erasca 0.22% Exit 0 $3.72 $947K −254,436 −$947K
BWAY - Brainsway 0.06% Exit 0 $19.05 $247K −12,965 −$247K
CATX - Perspective Therapeutics 0.03% Exit 0 $2.76 $138K −50,000 −$138K

* Reported price is value ÷ shares from the 13F as of period end — not a live market quote. Weight % is each long-equity position ÷ full 13F AUM, so rows may not sum to 100% when the filing includes options or other non-equity (excluded from this table). Share change and $ change are vs 2025 Q4. Click column headers to sort · click New / Hold / Add / Reduce to promote that move type to the top. Exit opens the last-held block below.

Filings history

20 periods · normalized AUM · open a period for holdings

Period Holdings AUM QoQ Form Filed Filing ID
2026 Q2 88 $524M +19.1% 13F-HR 8/14/2026 000138993326000006
2026 Q1 83 $440M +2.1% 13F-HR 5/15/2026 000138993326000004
2025 Q4 77 $431M +6.4% 13F-HR 2/17/2026 000138993326000002
2025 Q3 75 $405M +11.9% 13F-HR 11/14/2025 000138993325000008
2025 Q2 76 $362M +2.5% 13F-HR 8/14/2025 000138993225000011
2025 Q1 83 $353M −10.2% 13F-HR 5/15/2025 000138993325000002
2024 Q4 82 $393M −7.1% 13F-HR 2/14/2025 000138993225000004
2024 Q3 84 $423M +1.0% 13F-HR 11/14/2024 000138993224000020
2024 Q2 83 $419M −4.6% 13F-HR 8/14/2024 000138993224000016
2024 Q1 72 $439M +5.3% 13F-HR 5/15/2024 000138993224000012
2023 Q4 76 $417M +29.9% 13F-HR 2/14/2024 000138993224000004
2023 Q3 75 $321M −12.3% 13F-HR 11/14/2023 000138993223000010
2023 Q2 73 $366M +9.6% 13F-HR 8/14/2023 000138993323000008
2023 Q1 72 $334M −5.9% 13F-HR 5/15/2023 000138993323000006
2022 Q4 79 $355M −4.6% 13F-HR 2/14/2023 000138993323000002
2022 Q3 87 $372M +1.4% 13F-HR 11/14/2022 000138993322000010
2022 Q2 90 $367M −4.4% 13F-HR 8/15/2022 000138993322000008
2022 Q1 94 $384M −3.5% 13F-HR 5/16/2022 000138993322000006
2021 Q4 87 $398M +5.6% 13F-HR 2/14/2022 000138993322000002
2021 Q3 80 $377M 13F-HR 11/15/2021 000138993321000011

About

DAFNA Capital Management LLC

20 processed 13Fs on this site · 2021 Q3–2026 Q2

Entity
DAFNA Capital Management LLC
Notable person
Nathan Fischel
Location
Los Angeles, CA
All SEC filings
View on sec.gov