Follow-The-Filings

Featured 13F manager

DAFNA Capital Management LLC Nathan Fischel

Los Angeles, CA 20 processed 13Fs on this site · 2021 Q3–2026 Q2

  • $524M
  • 88 Positions
  • 2026 Q2
  • +19.1% QoQ
  • Top 5 40.2%

Nathan Fischel files DAFNA Capital Management LLC as a Form 13F. The latest book is 2026 Q2 at $524M, up 19.1% QoQ, led by Revolution Medicines, Spdr S&P Biotech ETF, and Compass Pathways.

Portfolio

2026 Q2 · filed 8/14/2026 · 88 long · top 12 shown

top 5 40.2% · top 10 56.2%

AUM over time

2026 Q2 $524M +19.1% QoQ
2021 Q3 · $377M 2021 Q3 · $377M
Q3 2021
2021 Q4 · $398M · +5.6% QoQ 2021 Q4 · $398M · +5.6% QoQ
Q4
2022 Q1 · $384M · −3.5% QoQ 2022 Q1 · $384M · −3.5% QoQ
Q1 2022
2022 Q2 · $367M · −4.4% QoQ 2022 Q2 · $367M · −4.4% QoQ
Q2
2022 Q3 · $372M · +1.4% QoQ 2022 Q3 · $372M · +1.4% QoQ
Q3
2022 Q4 · $355M · −4.6% QoQ 2022 Q4 · $355M · −4.6% QoQ
Q4
2023 Q1 · $334M · −5.9% QoQ 2023 Q1 · $334M · −5.9% QoQ
Q1 2023
2023 Q2 · $366M · +9.6% QoQ 2023 Q2 · $366M · +9.6% QoQ
Q2
2023 Q3 · $321M · −12.3% QoQ 2023 Q3 · $321M · −12.3% QoQ
Q3
2023 Q4 · $417M · +29.9% QoQ 2023 Q4 · $417M · +29.9% QoQ
Q4
2024 Q1 · $439M · +5.3% QoQ 2024 Q1 · $439M · +5.3% QoQ
Q1 2024
2024 Q2 · $419M · −4.6% QoQ 2024 Q2 · $419M · −4.6% QoQ
Q2
2024 Q3 · $423M · +1.0% QoQ 2024 Q3 · $423M · +1.0% QoQ
Q3
2024 Q4 · $393M · −7.1% QoQ 2024 Q4 · $393M · −7.1% QoQ
Q4
2025 Q1 · $353M · −10.2% QoQ 2025 Q1 · $353M · −10.2% QoQ
Q1 2025
2025 Q2 · $362M · +2.5% QoQ 2025 Q2 · $362M · +2.5% QoQ
Q2
2025 Q3 · $405M · +11.9% QoQ 2025 Q3 · $405M · +11.9% QoQ
Q3
2025 Q4 · $431M · +6.4% QoQ 2025 Q4 · $431M · +6.4% QoQ
Q4
2026 Q1 · $440M · +2.1% QoQ 2026 Q1 · $440M · +2.1% QoQ
Q1 2026
2026 Q2 · $524M · +19.1% QoQ 2026 Q2 · $524M · +19.1% QoQ
Q2

Book

2022 Q3 2022 Q2 · filed 14 Nov · long equity

XBI - Spdr Sp Biotech ETF 12.07% Reduce −7.7% 566,000 $79.32 $45M −47,000 −$633K
STXS - Stereotaxis 6.62% Hold 13,680,554 $1.80 $25M
Blueprint Medicines 4.63% Reduce 0.0% 261,235 $65.89 $17M −45 +$4M
BHVN - Biohaven 4.48% Hold 110,100 $151.17 $17M
ASND - Ascendis Pharma A/S 3.77% Reduce −2.5% 135,712 $103.26 $14M −3,500 +$1M
XENE - Xenon Pharmaceuticals 3.64% Reduce −14.5% 375,223 $36.10 $14M −63,400 +$203K
Adicet Bio 3.58% Hold 935,766 $14.22 $13M
FATE - Fate Therapeutics 3.25% Reduce −2.0% 539,940 $22.41 $12M −11,000 −$2M
NDAQ - Nasdaq Omx 3.22% Hold 102,500 $116.96 $12M
RVMD - Revolution Medicines 2.54% Add +60.0% 479,785 $19.72 $9M +180,000 +$4M
CYTK - Cytokinetics 2.40% Reduce −13.0% 183,995 $48.45 $9M −27,500 +$605K
SNDX - Syndax Pharmaceuticals 2.30% Reduce −4.2% 355,487 $24.03 $9M −15,500 +$1M
NBIX - Neurocrine Biosciences 2.29% Reduce −3.0% 80,155 $106.21 $9M −2,500 +$456K
IDYA - Ideaya Biosciences 2.16% Reduce −1.8% 538,561 $14.92 $8M −10,000 +$465K
EWTX - Edgewise Therapeutics 2.07% Add +12.2% 781,112 $9.84 $8M +85,153 +$2M
NRIX - Nurix Therapeutics 1.99% Hold 566,695 $13.03 $7M
Iveric Bio 1.94% Reduce −0.2% 401,476 $17.94 $7M −1,000 +$3M
Sage Therapeutics 1.90% Hold 180,306 $39.16 $7M
Karuna Therapeutics 1.75% Reduce −53.4% 28,886 $224.92 $6M −33,167 −$1M
Cymabay Therapeutics 1.60% Reduce −4.7% 1,703,235 $3.50 $6M −84,334 +$688K
DXCM - Dexcom 1.57% Hold 72,552 $80.54 $6M
Merus 1.49% Add +5.3% 276,893 $20.03 $6M +14,002 −$406K
Morphic 1.49% Hold 195,467 $28.30 $6M
ALEC - Alector 1.35% Reduce −3.6% 532,438 $9.46 $5M −20,000 −$576K
Mirati Therapeutics 1.35% Reduce −10.1% 71,600 $69.85 $5M −8,000 −$343K
IPSC - Century Therapeutics 1.26% Hold 475,367 $9.89 $5M
RCUS - Arcus Biosciences 1.26% Reduce −4.8% 178,717 $26.16 $5M −9,000 −$82K
Aerie Pharmaceuticals 1.25% Add +6.3% 307,232 $15.13 $5M +18,192 +$2M
APLSUSD - Apellis Pharmaceuticals 1.21% Reduce −32.0% 65,946 $68.30 $5M −30,989 +$121K
Cardiovascular Sys 1.07% Hold 286,988 $13.86 $4M
AXGN - Axogen 1.06% Hold 332,103 $11.92 $4M
89BIO 1.02% Reduce −14.6% 654,862 $5.79 $4M −111,912 +$1M
Kalvista Pharmaceuticals 1.00% Reduce −3.9% 255,313 $14.51 $4M −10,350 +$1M
F-Star Therapeutics 0.79% Hold 576,881 $5.12 $3M
BCYC - Bicycle Therapeutics 0.76% Reduce −6.9% 122,200 $23.26 $3M −9,000 +$640K
KURA - Kura Oncology 0.76% Add +75.1% 206,329 $13.66 $3M +88,500 +$658K
ATRC - Atricure 0.76% Hold 72,029 $39.10 $3M
Mersana Therapeutics 0.69% Reduce −7.1% 377,763 $6.76 $3M −29,000 +$675K
Mediwound 0.53% New 1,428,571 $1.39 $2M +1,428,571 +$2M
Vigil Neuroscience 0.53% Add +116.9% 216,395 $9.10 $2M +116,641 +$2M
ARAY - Accuray 0.53% Hold 941,800 $2.08 $2M
Iteos Therapeutics 0.50% Reduce −7.3% 97,560 $19.05 $2M −7,738 −$310K
LRMR - Larimar Therapeutics 0.49% Add +1050.1% 574,996 $3.20 $2M +525,000 +$2M
LKFT - Galapagos 0.49% Hold 42,675 $42.65 $2M
Syros Pharmaceuticals 0.46% New 265,878 $6.44 $2M +265,878 +$2M
Dice Therapeutics 0.43% Reduce −50.0% 78,500 $20.28 $2M −78,404 −$843K
VKTX - Viking Therapeutics 0.40% Add +19.5% 552,400 $2.72 $2M +90,000 +$167K
Keros Therapeutics 0.39% Hold 39,000 $37.62 $1M
Affimed 0.38% Hold 686,282 $2.06 $1M
ORIC - Oric Pharmaceuticals 0.36% Reduce −0.6% 413,526 $3.20 $1M −2,400 −$540K

Showing top 50 of 86 by value

Exits / last held

not current holdings · last reported size, unchanged · gone vs 2022 Q2

Stock % of portfolio Recent activity Shares Reported price* Value Share change $ change
Natus Medical 1.28% Exit 0 $32.77 $5M −143,600 −$5M
Holding 0.99% Exit 0 $75.25 $4M −48,452 −$4M
TCOM - Field Trip Health 0.44% Exit 0 $0.8403 $2M −1,904,141 −$2M
WVE - Wave Life Sciences 0.33% Exit 0 $3.25 $1M −372,361 −$1M
Radius Health 0.26% Exit 0 $10.37 $953K −91,935 −$953K
Rigel Pharmaceuticals 0.12% Exit 0 $1.13 $441K −390,066 −$441K
Lava Therapeutics 0.10% Exit 0 $2.95 $379K −128,335 −$379K
MDGL - Madrigal Pharmaceuticals 0.06% Exit 0 $71.61 $222K −3,100 −$222K
Connect Biopharma 0.06% Exit 0 $0.8720 $218K −250,000 −$218K
Aslan Pharmaceuticals 0.05% Exit 0 $0.4946 $170K −343,720 −$170K
ANNX - Annexon 0.04% Exit 0 $3.77 $154K −40,796 −$154K

* Reported price is value ÷ shares from the 13F as of period end — not a live market quote. Weight % is each long-equity position ÷ full 13F AUM, so rows may not sum to 100% when the filing includes options or other non-equity (excluded from this table). Share change and $ change are vs 2022 Q2. Click column headers to sort · click New / Hold / Add / Reduce to promote that move type to the top. Exit opens the last-held block below.

Filings history

20 periods · normalized AUM · open a period for holdings

Period Holdings AUM QoQ Form Filed Filing ID
2026 Q2 88 $524M +19.1% 13F-HR 8/14/2026 000138993326000006
2026 Q1 83 $440M +2.1% 13F-HR 5/15/2026 000138993326000004
2025 Q4 77 $431M +6.4% 13F-HR 2/17/2026 000138993326000002
2025 Q3 75 $405M +11.9% 13F-HR 11/14/2025 000138993325000008
2025 Q2 76 $362M +2.5% 13F-HR 8/14/2025 000138993225000011
2025 Q1 83 $353M −10.2% 13F-HR 5/15/2025 000138993325000002
2024 Q4 82 $393M −7.1% 13F-HR 2/14/2025 000138993225000004
2024 Q3 84 $423M +1.0% 13F-HR 11/14/2024 000138993224000020
2024 Q2 83 $419M −4.6% 13F-HR 8/14/2024 000138993224000016
2024 Q1 72 $439M +5.3% 13F-HR 5/15/2024 000138993224000012
2023 Q4 76 $417M +29.9% 13F-HR 2/14/2024 000138993224000004
2023 Q3 75 $321M −12.3% 13F-HR 11/14/2023 000138993223000010
2023 Q2 73 $366M +9.6% 13F-HR 8/14/2023 000138993323000008
2023 Q1 72 $334M −5.9% 13F-HR 5/15/2023 000138993323000006
2022 Q4 79 $355M −4.6% 13F-HR 2/14/2023 000138993323000002
2022 Q3 87 $372M +1.4% 13F-HR 11/14/2022 000138993322000010
2022 Q2 90 $367M −4.4% 13F-HR 8/15/2022 000138993322000008
2022 Q1 94 $384M −3.5% 13F-HR 5/16/2022 000138993322000006
2021 Q4 87 $398M +5.6% 13F-HR 2/14/2022 000138993322000002
2021 Q3 80 $377M 13F-HR 11/15/2021 000138993321000011

About

DAFNA Capital Management LLC

20 processed 13Fs on this site · 2021 Q3–2026 Q2

Entity
DAFNA Capital Management LLC
Notable person
Nathan Fischel
Location
Los Angeles, CA
All SEC filings
View on sec.gov