Follow-The-Filings

Featured 13F manager

DAFNA Capital Management LLC Nathan Fischel

Los Angeles, CA 20 processed 13Fs on this site · 2021 Q3–2026 Q2

  • $524M
  • 88 Positions
  • 2026 Q2
  • +19.1% QoQ
  • Top 5 40.2%

Nathan Fischel files DAFNA Capital Management LLC as a Form 13F. The latest book is 2026 Q2 at $524M, up 19.1% QoQ, led by Revolution Medicines, Spdr S&P Biotech ETF, and Compass Pathways.

Portfolio

2026 Q2 · filed 8/14/2026 · 88 long · top 12 shown

top 5 40.2% · top 10 56.2%

AUM over time

2026 Q2 $524M +19.1% QoQ
2021 Q3 · $377M 2021 Q3 · $377M
Q3 2021
2021 Q4 · $398M · +5.6% QoQ 2021 Q4 · $398M · +5.6% QoQ
Q4
2022 Q1 · $384M · −3.5% QoQ 2022 Q1 · $384M · −3.5% QoQ
Q1 2022
2022 Q2 · $367M · −4.4% QoQ 2022 Q2 · $367M · −4.4% QoQ
Q2
2022 Q3 · $372M · +1.4% QoQ 2022 Q3 · $372M · +1.4% QoQ
Q3
2022 Q4 · $355M · −4.6% QoQ 2022 Q4 · $355M · −4.6% QoQ
Q4
2023 Q1 · $334M · −5.9% QoQ 2023 Q1 · $334M · −5.9% QoQ
Q1 2023
2023 Q2 · $366M · +9.6% QoQ 2023 Q2 · $366M · +9.6% QoQ
Q2
2023 Q3 · $321M · −12.3% QoQ 2023 Q3 · $321M · −12.3% QoQ
Q3
2023 Q4 · $417M · +29.9% QoQ 2023 Q4 · $417M · +29.9% QoQ
Q4
2024 Q1 · $439M · +5.3% QoQ 2024 Q1 · $439M · +5.3% QoQ
Q1 2024
2024 Q2 · $419M · −4.6% QoQ 2024 Q2 · $419M · −4.6% QoQ
Q2
2024 Q3 · $423M · +1.0% QoQ 2024 Q3 · $423M · +1.0% QoQ
Q3
2024 Q4 · $393M · −7.1% QoQ 2024 Q4 · $393M · −7.1% QoQ
Q4
2025 Q1 · $353M · −10.2% QoQ 2025 Q1 · $353M · −10.2% QoQ
Q1 2025
2025 Q2 · $362M · +2.5% QoQ 2025 Q2 · $362M · +2.5% QoQ
Q2
2025 Q3 · $405M · +11.9% QoQ 2025 Q3 · $405M · +11.9% QoQ
Q3
2025 Q4 · $431M · +6.4% QoQ 2025 Q4 · $431M · +6.4% QoQ
Q4
2026 Q1 · $440M · +2.1% QoQ 2026 Q1 · $440M · +2.1% QoQ
Q1 2026
2026 Q2 · $524M · +19.1% QoQ 2026 Q2 · $524M · +19.1% QoQ
Q2

Book

2025 Q1 2024 Q4 · filed 15 May · long equity

XBI - Spdr S&P Biotech ETF 9.30% Add +1.8% 404,505 $81.10 $33M +7,000 −$3M
STXS - Stereotaxis 6.83% Hold 13,680,554 $1.76 $24M
RVMD - Revolution Medicines 6.58% Add +4.0% 656,176 $35.36 $23M +25,000 −$4M
Merus 5.51% Add +2.2% 461,804 $42.09 $19M +10,000 +$439K
ATRC - Atricure 5.42% Reduce −7.7% 592,273 $32.26 $19M −49,400 −$503K
CYTK - Cytokinetics 4.54% Hold 398,100 $40.19 $16M
Blueprint Medicines 3.82% Add +1.7% 152,263 $88.51 $13M +2,500 +$414K
NDAQ - Ishares Nasdaq Biotech Indx 3.72% Hold 102,500 $127.90 $13M
AXGN - Axogen 3.57% Reduce −19.6% 680,782 $18.50 $13M −166,100 −$1M
ASND - Ascendis Pharma A/S 3.55% Reduce −22.2% 80,398 $155.86 $13M −22,957 −$2M
IDYA - Ideaya Biosciences 2.74% Add +18.1% 589,330 $16.38 $10M +90,503 −$3M
XENE - Xenon Pharmaceuticals 2.60% Hold 273,739 $33.55 $9M
Kalvista Pharmaceuticals 2.46% Reduce −7.3% 752,359 $11.54 $9M −59,319 +$2M
NBIX - Neurocrine Biosciences 2.25% Hold 71,615 $110.60 $8M
SNDX - Syndax Pharmaceuticals 1.90% Add +0.5% 544,502 $12.28 $7M +2,500 −$476K
DAWNGBX — 1.64% Hold 731,363 $7.93 $6M
TNDM - Tandem Diabetes Care 1.60% Add +31.8% 294,208 $19.16 $6M +71,000 −$2M
URGN - Urogen Pharma 1.54% Hold 492,515 $11.06 $5M
BHVN - Biohaven 1.50% Hold 220,235 $24.04 $5M
MLYS - Mineralys Therapeutics 1.39% Add +111.1% 309,200 $15.88 $5M +162,700 +$3M
RCUS - Arcus Biosciences 1.39% Add +145.9% 625,126 $7.85 $5M +370,909 +$1M
DXCM - Dexcom 1.27% Hold 65,552 $68.29 $4M
BCRX - Biocryst Pharmaceuticals 1.19% Reduce −16.3% 558,255 $7.50 $4M −108,745 −$829K
EWTX - Edgewise Therapeutics 1.14% Reduce −2.1% 183,140 $22.00 $4M −4,000 −$968K
LKFT - Galapagos 0.93% Hold 130,175 $25.12 $3M
INGN - Inogen 0.93% Add +119.4% 458,065 $7.13 $3M +249,275 +$1M
PODD - Insulet 0.89% Reduce −4.0% 11,900 $262.61 $3M −500 −$112K
ALKS - Alkermes 0.88% Reduce −22.0% 94,200 $33.02 $3M −26,500 −$361K
KURA - Kura Oncology 0.87% Add +3.3% 463,368 $6.60 $3M +15,000 −$847K
STOK - Stoke Therapeutics 0.84% Add +159.5% 443,998 $6.65 $3M +272,901 +$1M
IMVT - Immunovant 0.82% Add +57.4% 169,996 $17.09 $3M +62,000 +$230K
BCAX - Bicara Therapeutics 0.78% Add +100.9% 212,001 $13.03 $3M +106,501 +$925K
ARAY - Accuray 0.62% Hold 1,222,358 $1.79 $2M
2seventy Bio 0.60% Hold 429,252 $4.94 $2M
PRQR - Proqr Therapeutics 0.59% Hold 1,567,561 $1.33 $2M
CMPS - Compass Pathways 0.58% Add +192.4% 711,046 $2.86 $2M +467,836 +$1M
ALLO - Allogene Therapeutics 0.57% Add +11.3% 1,380,118 $1.46 $2M +140,000 −$626K
TELA - Tela Bio 0.50% Hold 1,441,029 $1.22 $2M
ALGN - Align Technology 0.50% Add +100.0% 11,000 $158.86 $2M +5,500 +$601K
DNLI - Denali Therapeutics 0.49% New 127,900 $13.60 $2M +127,900 +$2M
CATBUSD - Astria Therapeutics 0.48% Add +5.0% 314,775 $5.34 $2M +15,000 −$999K
VKTX - Viking Therapeutics 0.44% Hold 64,516 $24.15 $2M
Regulus Therapeutics 0.42% Reduce −3.2% 847,176 $1.75 $1M −28,024 +$100K
BWAY - Brainsway 0.42% Reduce −19.0% 156,533 $9.47 $1M −36,675 −$340K
ORIC - Oric Pharmaceuticals 0.38% New 242,000 $5.58 $1M +242,000 +$1M
Keros Therapeutics 0.38% Hold 130,316 $10.19 $1M
LXEO - Lexeo Therapeutics 0.37% Reduce −3.8% 378,083 $3.47 $1M −15,000 −$1M
Iteos Therapeutics 0.36% Add +13.3% 213,347 $5.97 $1M +25,000 −$173K
PVLA - Palvella Therapeutics 0.34% Reduce −39.3% 43,348 $27.99 $1M −28,104 +$356K
SPRY - Ars Pharmaceuticals 0.34% Add +7.3% 95,290 $12.58 $1M +6,500 +$262K

Showing top 50 of 82 by value

Exits / last held

not current holdings · last reported size, unchanged · gone vs 2024 Q4

Stock % of portfolio Recent activity Shares Reported price* Value Share change $ change
CNTA - Centessa Pharmaceuticals 0.20% Exit 0 $16.75 $795K −47,453 −$795K
VIR - Vir Biotechnology 0.19% Exit 0 $7.34 $734K −100,000 −$734K
ACRV - Acrivon Therapeutics 0.17% Exit 0 $6.02 $677K −112,414 −$677K
Masimo 0.13% Exit 0 $165.33 $496K −3,000 −$496K
CATX - Perspective Therapeutics 0.11% Exit 0 $3.19 $415K −130,169 −$415K
Acelyrin 0.07% Exit 0 $3.14 $276K −87,989 −$276K
CMPX - Compass Therapeutics 0.06% Exit 0 $1.45 $230K −158,394 −$230K

* Reported price is value ÷ shares from the 13F as of period end — not a live market quote. Weight % is each long-equity position ÷ full 13F AUM, so rows may not sum to 100% when the filing includes options or other non-equity (excluded from this table). Share change and $ change are vs 2024 Q4. Click column headers to sort · click New / Hold / Add / Reduce to promote that move type to the top. Exit opens the last-held block below.

Filings history

20 periods · normalized AUM · open a period for holdings

Period Holdings AUM QoQ Form Filed Filing ID
2026 Q2 88 $524M +19.1% 13F-HR 8/14/2026 000138993326000006
2026 Q1 83 $440M +2.1% 13F-HR 5/15/2026 000138993326000004
2025 Q4 77 $431M +6.4% 13F-HR 2/17/2026 000138993326000002
2025 Q3 75 $405M +11.9% 13F-HR 11/14/2025 000138993325000008
2025 Q2 76 $362M +2.5% 13F-HR 8/14/2025 000138993225000011
2025 Q1 83 $353M −10.2% 13F-HR 5/15/2025 000138993325000002
2024 Q4 82 $393M −7.1% 13F-HR 2/14/2025 000138993225000004
2024 Q3 84 $423M +1.0% 13F-HR 11/14/2024 000138993224000020
2024 Q2 83 $419M −4.6% 13F-HR 8/14/2024 000138993224000016
2024 Q1 72 $439M +5.3% 13F-HR 5/15/2024 000138993224000012
2023 Q4 76 $417M +29.9% 13F-HR 2/14/2024 000138993224000004
2023 Q3 75 $321M −12.3% 13F-HR 11/14/2023 000138993223000010
2023 Q2 73 $366M +9.6% 13F-HR 8/14/2023 000138993323000008
2023 Q1 72 $334M −5.9% 13F-HR 5/15/2023 000138993323000006
2022 Q4 79 $355M −4.6% 13F-HR 2/14/2023 000138993323000002
2022 Q3 87 $372M +1.4% 13F-HR 11/14/2022 000138993322000010
2022 Q2 90 $367M −4.4% 13F-HR 8/15/2022 000138993322000008
2022 Q1 94 $384M −3.5% 13F-HR 5/16/2022 000138993322000006
2021 Q4 87 $398M +5.6% 13F-HR 2/14/2022 000138993322000002
2021 Q3 80 $377M 13F-HR 11/15/2021 000138993321000011

About

DAFNA Capital Management LLC

20 processed 13Fs on this site · 2021 Q3–2026 Q2

Entity
DAFNA Capital Management LLC
Notable person
Nathan Fischel
Location
Los Angeles, CA
All SEC filings
View on sec.gov