Follow-The-Filings

Featured 13F manager

DAFNA Capital Management LLC Nathan Fischel

Los Angeles, CA 20 processed 13Fs on this site · 2021 Q3–2026 Q2

  • $524M
  • 88 Positions
  • 2026 Q2
  • +19.1% QoQ
  • Top 5 40.2%

Nathan Fischel files DAFNA Capital Management LLC as a Form 13F. The latest book is 2026 Q2 at $524M, up 19.1% QoQ, led by Revolution Medicines, Spdr S&P Biotech ETF, and Compass Pathways.

Portfolio

2026 Q2 · filed 8/14/2026 · 88 long · top 12 shown

top 5 40.2% · top 10 56.2%

AUM over time

2026 Q2 $524M +19.1% QoQ
2021 Q3 · $377M 2021 Q3 · $377M
Q3 2021
2021 Q4 · $398M · +5.6% QoQ 2021 Q4 · $398M · +5.6% QoQ
Q4
2022 Q1 · $384M · −3.5% QoQ 2022 Q1 · $384M · −3.5% QoQ
Q1 2022
2022 Q2 · $367M · −4.4% QoQ 2022 Q2 · $367M · −4.4% QoQ
Q2
2022 Q3 · $372M · +1.4% QoQ 2022 Q3 · $372M · +1.4% QoQ
Q3
2022 Q4 · $355M · −4.6% QoQ 2022 Q4 · $355M · −4.6% QoQ
Q4
2023 Q1 · $334M · −5.9% QoQ 2023 Q1 · $334M · −5.9% QoQ
Q1 2023
2023 Q2 · $366M · +9.6% QoQ 2023 Q2 · $366M · +9.6% QoQ
Q2
2023 Q3 · $321M · −12.3% QoQ 2023 Q3 · $321M · −12.3% QoQ
Q3
2023 Q4 · $417M · +29.9% QoQ 2023 Q4 · $417M · +29.9% QoQ
Q4
2024 Q1 · $439M · +5.3% QoQ 2024 Q1 · $439M · +5.3% QoQ
Q1 2024
2024 Q2 · $419M · −4.6% QoQ 2024 Q2 · $419M · −4.6% QoQ
Q2
2024 Q3 · $423M · +1.0% QoQ 2024 Q3 · $423M · +1.0% QoQ
Q3
2024 Q4 · $393M · −7.1% QoQ 2024 Q4 · $393M · −7.1% QoQ
Q4
2025 Q1 · $353M · −10.2% QoQ 2025 Q1 · $353M · −10.2% QoQ
Q1 2025
2025 Q2 · $362M · +2.5% QoQ 2025 Q2 · $362M · +2.5% QoQ
Q2
2025 Q3 · $405M · +11.9% QoQ 2025 Q3 · $405M · +11.9% QoQ
Q3
2025 Q4 · $431M · +6.4% QoQ 2025 Q4 · $431M · +6.4% QoQ
Q4
2026 Q1 · $440M · +2.1% QoQ 2026 Q1 · $440M · +2.1% QoQ
Q1 2026
2026 Q2 · $524M · +19.1% QoQ 2026 Q2 · $524M · +19.1% QoQ
Q2

Book

2022 Q4 2022 Q3 · filed 14 Feb · long equity

XBI - Spdr S&P Biotech ETF 13.23% Hold 566,000 $83.00 $47M
STXS - Stereotaxis 7.98% Hold 13,680,554 $2.07 $28M
ASND - Ascendis Pharma A/S 4.48% Reduce −4.1% 130,212 $122.13 $16M −5,500 +$2M
Karuna Therapeutics 3.99% Add +149.3% 72,027 $196.50 $14M +43,141 +$8M
NDAQ - Ishares Nasdaq Biotech Indx 3.79% Hold 102,500 $131.29 $13M
Iveric Bio 3.65% Add +50.9% 605,975 $21.41 $13M +204,499 +$6M
XENE - Xenon Pharmaceuticals 3.51% Reduce −15.8% 316,092 $39.43 $12M −59,131 −$1M
Blueprint Medicines 3.22% Hold 261,235 $43.81 $11M
RVMD - Revolution Medicines 3.21% Reduce −0.4% 477,785 $23.82 $11M −2,000 +$2M
SNDX - Syndax Pharmaceuticals 3.20% Add +25.8% 447,073 $25.45 $11M +91,586 +$3M
NBIX - Neurocrine Biosciences 2.46% Reduce −8.8% 73,121 $119.44 $9M −7,034 +$221K
IDYA - Ideaya Biosciences 2.40% Reduce −13.0% 468,358 $18.17 $9M −70,203 +$475K
CYTK - Cytokinetics 2.37% Hold 183,995 $45.82 $8M
DXCM - Dexcom 2.15% Reduce −6.9% 67,552 $113.24 $8M −5,000 +$2M
Sage Therapeutics 1.94% Hold 180,306 $38.14 $7M
EWTX - Edgewise Therapeutics 1.93% Reduce −1.8% 766,843 $8.94 $7M −14,269 −$830K
NRIX - Nurix Therapeutics 1.75% Hold 566,695 $10.98 $6M
Adicet Bio 1.59% Reduce −32.5% 631,554 $8.94 $6M −304,212 −$8M
FATE - Fate Therapeutics 1.57% Add +2.0% 550,940 $10.09 $6M +11,000 −$7M
BHVN - Biohaven 1.54% Add +156.0% 393,113 $13.88 $5M +239,549 +$4M
Morphic 1.47% Hold 195,467 $26.75 $5M
ALEC - Alector 1.38% Hold 532,438 $9.23 $5M
VKTX - Viking Therapeutics 1.38% Reduce −5.6% 521,553 $9.40 $5M −30,847 +$3M
APLSUSD - Apellis Pharmaceuticals 1.22% Add +26.5% 83,446 $51.71 $4M +17,500 −$189K
Merus 1.18% Reduce −2.5% 269,893 $15.47 $4M −7,000 −$1M
Kalvista Pharmaceuticals 1.17% Add +141.3% 616,032 $6.76 $4M +360,719 +$459K
89BIO 1.16% Reduce −50.5% 324,173 $12.73 $4M −330,689 +$335K
Cardiovascular Systems 1.10% Hold 286,988 $13.62 $4M
Dice Therapeutics 1.09% Add +57.3% 123,500 $31.20 $4M +45,000 +$2M
F-Star Therapeutics 1.03% Hold 576,881 $6.32 $4M
BCYC - Bicycle Therapeutics 1.02% Hold 122,200 $29.60 $4M
Mirati Therapeutics 0.94% Add +2.8% 73,600 $45.31 $3M +2,000 −$2M
AXGN - Axogen 0.93% Hold 332,103 $9.98 $3M
ATRC - Atricure 0.90% Hold 72,029 $44.38 $3M
CMPX - Compass Therapeutics 0.85% Add +220.1% 602,051 $5.03 $3M +413,957 +$3M
RCUS - Arcus Biosciences 0.83% Reduce −20.4% 142,217 $20.68 $3M −36,500 −$2M
BCRX - Biocryst Pharmaceuticals 0.81% New 251,000 $11.48 $3M +251,000 +$3M
Mediwound 0.78% New 204,082 $13.49 $3M +204,082 +$3M
ARAY - Accuray 0.72% Add +29.8% 1,222,358 $2.09 $3M +280,558 +$596K
IPSC - Century Therapeutics 0.69% Hold 475,367 $5.13 $2M
Mersana Therapeutics 0.68% Add +9.5% 413,463 $5.86 $2M +35,700 −$131K
LKFT - Galapagos 0.66% Add +23.4% 52,675 $44.38 $2M +10,000 +$518K
AUTL - Autolus Therapeutics 0.63% Add +137.1% 1,176,150 $1.90 $2M +680,000 +$1M
Neuronetics 0.61% Hold 313,717 $6.87 $2M
Vigil Neuroscience 0.59% Reduce −22.0% 168,846 $12.50 $2M −47,549 +$142K
LRMR - Larimar Therapeutics 0.55% Reduce −17.7% 473,136 $4.13 $2M −101,860 +$114K
Iteos Therapeutics 0.54% Add +1.0% 98,560 $19.53 $2M +1,000 +$66K
KURA - Kura Oncology 0.51% Reduce −29.8% 144,784 $12.41 $2M −61,545 −$1M
Keros Therapeutics 0.45% Reduce −15.4% 33,000 $48.02 $2M −6,000 +$118K
ORIC - Oric Pharmaceuticals 0.44% Reduce −36.1% 264,237 $5.89 $2M −149,289 +$233K

Showing top 50 of 79 by value

Exits / last held

not current holdings · last reported size, unchanged · gone vs 2022 Q3

Stock % of portfolio Recent activity Shares Reported price* Value Share change $ change
BHVN - Biohaven 4.48% Exit 0 $151.17 $17M −110,100 −$17M
Aerie Pharmaceuticals 1.25% Exit 0 $15.13 $5M −307,232 −$5M
Mediwound 0.53% Exit 0 $1.39 $2M −1,428,571 −$2M
Ngm Biopharmaceuticals 0.26% Exit 0 $13.07 $980K −74,953 −$980K
Gamida Cell 0.26% Exit 0 $1.59 $978K −614,896 −$978K
Mei Pharma 0.18% Exit 0 $0.3865 $683K −1,767,146 −$683K
Gh Research 0.16% Exit 0 $11.63 $612K −52,631 −$612K
CMPS - Compass Pathways 0.14% Exit 0 $10.72 $508K −47,390 −$508K
PRQR - Proqr Therapeutics 0.13% Exit 0 $0.7438 $483K −649,383 −$483K
Sutro Biopharma 0.12% Exit 0 $5.55 $451K −81,200 −$451K
Otonomy 0.12% Exit 0 $0.2952 $434K −1,470,199 −$434K
Venus Concept 0.11% Exit 0 $0.4400 $426K −968,187 −$426K

* Reported price is value ÷ shares from the 13F as of period end — not a live market quote. Weight % is each long-equity position ÷ full 13F AUM, so rows may not sum to 100% when the filing includes options or other non-equity (excluded from this table). Share change and $ change are vs 2022 Q3. Click column headers to sort · click New / Hold / Add / Reduce to promote that move type to the top. Exit opens the last-held block below.

Filings history

20 periods · normalized AUM · open a period for holdings

Period Holdings AUM QoQ Form Filed Filing ID
2026 Q2 88 $524M +19.1% 13F-HR 8/14/2026 000138993326000006
2026 Q1 83 $440M +2.1% 13F-HR 5/15/2026 000138993326000004
2025 Q4 77 $431M +6.4% 13F-HR 2/17/2026 000138993326000002
2025 Q3 75 $405M +11.9% 13F-HR 11/14/2025 000138993325000008
2025 Q2 76 $362M +2.5% 13F-HR 8/14/2025 000138993225000011
2025 Q1 83 $353M −10.2% 13F-HR 5/15/2025 000138993325000002
2024 Q4 82 $393M −7.1% 13F-HR 2/14/2025 000138993225000004
2024 Q3 84 $423M +1.0% 13F-HR 11/14/2024 000138993224000020
2024 Q2 83 $419M −4.6% 13F-HR 8/14/2024 000138993224000016
2024 Q1 72 $439M +5.3% 13F-HR 5/15/2024 000138993224000012
2023 Q4 76 $417M +29.9% 13F-HR 2/14/2024 000138993224000004
2023 Q3 75 $321M −12.3% 13F-HR 11/14/2023 000138993223000010
2023 Q2 73 $366M +9.6% 13F-HR 8/14/2023 000138993323000008
2023 Q1 72 $334M −5.9% 13F-HR 5/15/2023 000138993323000006
2022 Q4 79 $355M −4.6% 13F-HR 2/14/2023 000138993323000002
2022 Q3 87 $372M +1.4% 13F-HR 11/14/2022 000138993322000010
2022 Q2 90 $367M −4.4% 13F-HR 8/15/2022 000138993322000008
2022 Q1 94 $384M −3.5% 13F-HR 5/16/2022 000138993322000006
2021 Q4 87 $398M +5.6% 13F-HR 2/14/2022 000138993322000002
2021 Q3 80 $377M 13F-HR 11/15/2021 000138993321000011

About

DAFNA Capital Management LLC

20 processed 13Fs on this site · 2021 Q3–2026 Q2

Entity
DAFNA Capital Management LLC
Notable person
Nathan Fischel
Location
Los Angeles, CA
All SEC filings
View on sec.gov