Follow-The-Filings

Featured 13F manager

DAFNA Capital Management LLC Nathan Fischel

Los Angeles, CA 20 processed 13Fs on this site · 2021 Q3–2026 Q2

  • $524M
  • 88 Positions
  • 2026 Q2
  • +19.1% QoQ
  • Top 5 40.2%

Nathan Fischel files DAFNA Capital Management LLC as a Form 13F. The latest book is 2026 Q2 at $524M, up 19.1% QoQ, led by Revolution Medicines, Spdr S&P Biotech ETF, and Compass Pathways.

Portfolio

2026 Q2 · filed 8/14/2026 · 88 long · top 12 shown

top 5 40.2% · top 10 56.2%

AUM over time

2026 Q2 $524M +19.1% QoQ
2021 Q3 · $377M 2021 Q3 · $377M
Q3 2021
2021 Q4 · $398M · +5.6% QoQ 2021 Q4 · $398M · +5.6% QoQ
Q4
2022 Q1 · $384M · −3.5% QoQ 2022 Q1 · $384M · −3.5% QoQ
Q1 2022
2022 Q2 · $367M · −4.4% QoQ 2022 Q2 · $367M · −4.4% QoQ
Q2
2022 Q3 · $372M · +1.4% QoQ 2022 Q3 · $372M · +1.4% QoQ
Q3
2022 Q4 · $355M · −4.6% QoQ 2022 Q4 · $355M · −4.6% QoQ
Q4
2023 Q1 · $334M · −5.9% QoQ 2023 Q1 · $334M · −5.9% QoQ
Q1 2023
2023 Q2 · $366M · +9.6% QoQ 2023 Q2 · $366M · +9.6% QoQ
Q2
2023 Q3 · $321M · −12.3% QoQ 2023 Q3 · $321M · −12.3% QoQ
Q3
2023 Q4 · $417M · +29.9% QoQ 2023 Q4 · $417M · +29.9% QoQ
Q4
2024 Q1 · $439M · +5.3% QoQ 2024 Q1 · $439M · +5.3% QoQ
Q1 2024
2024 Q2 · $419M · −4.6% QoQ 2024 Q2 · $419M · −4.6% QoQ
Q2
2024 Q3 · $423M · +1.0% QoQ 2024 Q3 · $423M · +1.0% QoQ
Q3
2024 Q4 · $393M · −7.1% QoQ 2024 Q4 · $393M · −7.1% QoQ
Q4
2025 Q1 · $353M · −10.2% QoQ 2025 Q1 · $353M · −10.2% QoQ
Q1 2025
2025 Q2 · $362M · +2.5% QoQ 2025 Q2 · $362M · +2.5% QoQ
Q2
2025 Q3 · $405M · +11.9% QoQ 2025 Q3 · $405M · +11.9% QoQ
Q3
2025 Q4 · $431M · +6.4% QoQ 2025 Q4 · $431M · +6.4% QoQ
Q4
2026 Q1 · $440M · +2.1% QoQ 2026 Q1 · $440M · +2.1% QoQ
Q1 2026
2026 Q2 · $524M · +19.1% QoQ 2026 Q2 · $524M · +19.1% QoQ
Q2

Book

2021 Q4 2021 Q3 · filed 14 Feb · long equity

STXS - Stereotaxis 21.33% Hold 13,680,554 $6.20 $85M
Blueprint Medicines 5.57% Hold 206,911 $107.11 $22M
FATE - Fate Therapeutics 5.48% Add +8.1% 372,160 $58.51 $22M +27,800 +$1M
Adicet Bio 3.22% Add +94.8% 733,172 $17.49 $13M +356,891 +$10M
XENE - Xenon Pharmaceuticals 3.16% Reduce −1.0% 402,667 $31.24 $13M −3,868 +$6M
Arena Pharmaceuticals 2.80% Hold 119,615 $92.94 $11M
IDYA - Ideaya Biosciences 2.73% Hold 460,061 $23.64 $11M
DXCM - Dexcom 2.45% Reduce −14.2% 18,138 $536.94 $10M −3,000 −$2M
Karuna Therapeutics 2.39% Reduce −2.9% 72,423 $130.99 $9M −2,162 +$363K
NRIX - Nurix Therapeutics 2.23% Hold 306,320 $28.95 $9M
Morphic 2.16% Hold 181,467 $47.38 $9M
BHVN - Biohaven 2.01% Reduce −34.1% 58,100 $137.81 $8M −30,000 −$4M
Sage Therapeutics 1.93% Hold 180,306 $42.54 $8M
Merus 1.81% Add +71.3% 226,089 $31.80 $7M +94,140 +$4M
NBIX - Neurocrine Biosciences 1.79% Reduce −1.2% 83,655 $85.17 $7M −1,000 −$994K
SNDX - Syndax Pharmaceuticals 1.63% Add +267.4% 296,535 $21.89 $6M +215,833 +$5M
NDAQ - Ishares Tr Nasdaq Biotech 1.57% Hold 40,900 $152.62 $6M
CYTK - Cytokinetics 1.54% Reduce −23.4% 134,094 $45.58 $6M −40,906 −$143K
Cymabay Therapeutics 1.52% Add +241.0% 1,787,569 $3.38 $6M +1,263,283 +$4M
Cardiovascular Sys 1.36% Add +48.1% 286,988 $18.78 $5M +93,247 −$971K
RVMD - Revolution Medicines 1.34% Add +1.2% 212,231 $25.17 $5M +2,500 −$428K
ATRC - Atricure 1.26% Hold 72,029 $69.53 $5M
RCUS - Arcus Biosciences 1.19% Reduce −5.3% 117,200 $40.47 $5M −6,500 +$430K
Mei Pharma 1.18% Add +175.3% 1,764,846 $2.67 $5M +1,123,846 +$3M
Iveric Bio 1.16% Add +27.6% 275,976 $16.72 $5M +59,625 +$1M
Otonomy 1.15% Reduce −7.5% 2,200,297 $2.08 $5M −179,095 +$9K
Natus Med 1.14% Add +99.3% 190,635 $23.73 $5M +94,982 +$2M
ARAY - Accuray 1.13% Hold 941,800 $4.77 $4M
Pardes Biosciences 0.96% New 233,500 $16.37 $4M +233,500 +$4M
F-Star Therapeutics 0.88% Hold 693,785 $5.02 $3M
ALEC - Alector 0.81% Add +44.5% 155,247 $20.65 $3M +47,835 +$755K
Affimed 0.79% Reduce −40.8% 571,282 $5.52 $3M −393,575 −$3M
AXGN - Axogen 0.78% New 332,103 $9.37 $3M +332,103 +$3M
Kalvista Pharmaceuticals 0.63% Add +0.8% 190,663 $13.23 $3M +1,500 −$779K
Iteos Therapeutics 0.63% Reduce −34.9% 54,090 $46.55 $3M −28,971 +$275K
LKFT - Galapagos 0.59% Reduce −45.1% 42,675 $55.14 $2M −35,000 −$2M
BMEA - Biomea Fusion 0.59% New 313,923 $7.45 $2M +313,923 +$2M
Rigel Pharmaceuticals 0.59% Add +8.7% 879,000 $2.65 $2M +70,000 −$608K
Holding 0.56% Add +10.7% 46,452 $47.71 $2M +4,500 −$571K
Athira Pharma 0.53% Hold 160,983 $13.03 $2M
VKTX - Viking Therapeutics 0.52% Hold 447,400 $4.60 $2M
Aerie Pharmaceuticals 0.51% Hold 289,040 $7.02 $2M
COGT - Cogent Biosciences 0.48% Hold 223,554 $8.58 $2M
89BIO 0.48% Add +14.2% 144,653 $13.07 $2M +18,001 −$590K
Kinnate Biopharma 0.47% Hold 106,453 $17.72 $2M
Mereo Biopharma Group 0.45% Hold 1,126,613 $1.60 $2M
Regulus Therapeutics 0.44% New 5,555,555 $0.3150 $2M +5,555,555 +$2M
Venus Concept 0.42% Reduce −12.4% 975,687 $1.70 $2M −137,541 −$1M
IPSC - Century Therapeutics 0.40% Add +25.2% 100,135 $15.86 $2M +20,135 −$425K
KURA - Kura Oncology 0.39% Add +9.9% 110,829 $14.00 $2M +10,000 −$337K

Showing top 50 of 85 by value

Exits / last held

not current holdings · last reported size, unchanged · gone vs 2021 Q3

Stock % of portfolio Recent activity Shares Reported price* Value Share change $ change
Dicerna Pharmaceuticals 3.14% Exit 0 $20.16 $12M −587,456 −$12M
Fs Development Ii · CL A 0.79% Exit 0 $9.95 $3M −299,950 −$3M
Kadmon 0.73% Exit 0 $8.71 $3M −314,561 −$3M
IFRX - Inflarx 0.41% Exit 0 $2.59 $2M −600,000 −$2M
Alpine Immune Sciences 0.32% Exit 0 $10.67 $1M −111,501 −$1M
Vascular Biogenics 0.03% Exit 0 $2.05 $113K −55,000 −$113K

* Reported price is value ÷ shares from the 13F as of period end — not a live market quote. Weight % is each long-equity position ÷ full 13F AUM, so rows may not sum to 100% when the filing includes options or other non-equity (excluded from this table). Share change and $ change are vs 2021 Q3. Click column headers to sort · click New / Hold / Add / Reduce to promote that move type to the top. Exit opens the last-held block below.

Filings history

20 periods · normalized AUM · open a period for holdings

Period Holdings AUM QoQ Form Filed Filing ID
2026 Q2 88 $524M +19.1% 13F-HR 8/14/2026 000138993326000006
2026 Q1 83 $440M +2.1% 13F-HR 5/15/2026 000138993326000004
2025 Q4 77 $431M +6.4% 13F-HR 2/17/2026 000138993326000002
2025 Q3 75 $405M +11.9% 13F-HR 11/14/2025 000138993325000008
2025 Q2 76 $362M +2.5% 13F-HR 8/14/2025 000138993225000011
2025 Q1 83 $353M −10.2% 13F-HR 5/15/2025 000138993325000002
2024 Q4 82 $393M −7.1% 13F-HR 2/14/2025 000138993225000004
2024 Q3 84 $423M +1.0% 13F-HR 11/14/2024 000138993224000020
2024 Q2 83 $419M −4.6% 13F-HR 8/14/2024 000138993224000016
2024 Q1 72 $439M +5.3% 13F-HR 5/15/2024 000138993224000012
2023 Q4 76 $417M +29.9% 13F-HR 2/14/2024 000138993224000004
2023 Q3 75 $321M −12.3% 13F-HR 11/14/2023 000138993223000010
2023 Q2 73 $366M +9.6% 13F-HR 8/14/2023 000138993323000008
2023 Q1 72 $334M −5.9% 13F-HR 5/15/2023 000138993323000006
2022 Q4 79 $355M −4.6% 13F-HR 2/14/2023 000138993323000002
2022 Q3 87 $372M +1.4% 13F-HR 11/14/2022 000138993322000010
2022 Q2 90 $367M −4.4% 13F-HR 8/15/2022 000138993322000008
2022 Q1 94 $384M −3.5% 13F-HR 5/16/2022 000138993322000006
2021 Q4 87 $398M +5.6% 13F-HR 2/14/2022 000138993322000002
2021 Q3 80 $377M 13F-HR 11/15/2021 000138993321000011

About

DAFNA Capital Management LLC

20 processed 13Fs on this site · 2021 Q3–2026 Q2

Entity
DAFNA Capital Management LLC
Notable person
Nathan Fischel
Location
Los Angeles, CA
All SEC filings
View on sec.gov