Follow-The-Filings

Featured 13F manager

DAFNA Capital Management LLC Nathan Fischel

Los Angeles, CA 20 processed 13Fs on this site · 2021 Q3–2026 Q2

  • $524M
  • 88 Positions
  • 2026 Q2
  • +19.1% QoQ
  • Top 5 40.2%

Nathan Fischel files DAFNA Capital Management LLC as a Form 13F. The latest book is 2026 Q2 at $524M, up 19.1% QoQ, led by Revolution Medicines, Spdr S&P Biotech ETF, and Compass Pathways.

Portfolio

2026 Q2 · filed 8/14/2026 · 88 long · top 12 shown

top 5 40.2% · top 10 56.2%

AUM over time

2026 Q2 $524M +19.1% QoQ
2021 Q3 · $377M 2021 Q3 · $377M
Q3 2021
2021 Q4 · $398M · +5.6% QoQ 2021 Q4 · $398M · +5.6% QoQ
Q4
2022 Q1 · $384M · −3.5% QoQ 2022 Q1 · $384M · −3.5% QoQ
Q1 2022
2022 Q2 · $367M · −4.4% QoQ 2022 Q2 · $367M · −4.4% QoQ
Q2
2022 Q3 · $372M · +1.4% QoQ 2022 Q3 · $372M · +1.4% QoQ
Q3
2022 Q4 · $355M · −4.6% QoQ 2022 Q4 · $355M · −4.6% QoQ
Q4
2023 Q1 · $334M · −5.9% QoQ 2023 Q1 · $334M · −5.9% QoQ
Q1 2023
2023 Q2 · $366M · +9.6% QoQ 2023 Q2 · $366M · +9.6% QoQ
Q2
2023 Q3 · $321M · −12.3% QoQ 2023 Q3 · $321M · −12.3% QoQ
Q3
2023 Q4 · $417M · +29.9% QoQ 2023 Q4 · $417M · +29.9% QoQ
Q4
2024 Q1 · $439M · +5.3% QoQ 2024 Q1 · $439M · +5.3% QoQ
Q1 2024
2024 Q2 · $419M · −4.6% QoQ 2024 Q2 · $419M · −4.6% QoQ
Q2
2024 Q3 · $423M · +1.0% QoQ 2024 Q3 · $423M · +1.0% QoQ
Q3
2024 Q4 · $393M · −7.1% QoQ 2024 Q4 · $393M · −7.1% QoQ
Q4
2025 Q1 · $353M · −10.2% QoQ 2025 Q1 · $353M · −10.2% QoQ
Q1 2025
2025 Q2 · $362M · +2.5% QoQ 2025 Q2 · $362M · +2.5% QoQ
Q2
2025 Q3 · $405M · +11.9% QoQ 2025 Q3 · $405M · +11.9% QoQ
Q3
2025 Q4 · $431M · +6.4% QoQ 2025 Q4 · $431M · +6.4% QoQ
Q4
2026 Q1 · $440M · +2.1% QoQ 2026 Q1 · $440M · +2.1% QoQ
Q1 2026
2026 Q2 · $524M · +19.1% QoQ 2026 Q2 · $524M · +19.1% QoQ
Q2

Book

2024 Q4 2024 Q3 · filed 14 Feb · long equity

XBI - Spdr S&P Biotech ETF 9.10% Reduce −1.0% 397,505 $90.06 $36M −4,000 −$4M
STXS - Stereotaxis 7.93% Hold 13,680,554 $2.28 $31M
RVMD - Revolution Medicines 7.02% Add +21.9% 631,176 $43.74 $28M +113,182 +$4M
ATRC - Atricure 4.98% Hold 641,673 $30.56 $20M
Merus 4.83% Add +9.5% 451,804 $42.05 $19M +39,231 −$2M
CYTK - Cytokinetics 4.76% Hold 398,100 $47.04 $19M
ASND - Ascendis Pharma A/S 3.62% Add +15.4% 103,355 $137.67 $14M +13,783 +$855K
AXGN - Axogen 3.55% Reduce −9.5% 846,882 $16.48 $14M −89,012 +$835K
NDAQ - Ishares Nasdaq Biotech Indx 3.44% Hold 102,500 $132.21 $14M
Blueprint Medicines 3.32% Add +23.0% 149,763 $87.22 $13M +28,000 +$2M
IDYA - Ideaya Biosciences 3.26% Add +5.8% 498,827 $25.70 $13M +27,417 −$2M
XENE - Xenon Pharmaceuticals 2.73% Hold 273,739 $39.20 $11M
NBIX - Neurocrine Biosciences 2.48% Add +2.9% 71,615 $136.50 $10M +2,000 +$2M
DAWNGBX — 2.36% Reduce −2.5% 731,363 $12.67 $9M −19,000 −$1M
BHVN - Biohaven 2.09% Add +17.7% 220,235 $37.35 $8M +33,105 −$1M
TNDM - Tandem Diabetes Care 2.04% Add +9.3% 223,208 $36.02 $8M +19,000 −$621K
SNDX - Syndax Pharmaceuticals 1.82% Add +2.9% 542,002 $13.22 $7M +15,300 −$3M
Kalvista Pharmaceuticals 1.75% Add +12.2% 811,678 $8.47 $7M +88,000 −$2M
URGN - Urogen Pharma 1.33% Add +7.3% 492,515 $10.65 $5M +33,600 −$583K
DXCM - Dexcom 1.30% Hold 65,552 $77.77 $5M
BCRX - Biocryst Pharmaceuticals 1.27% Hold 667,000 $7.52 $5M
EWTX - Edgewise Therapeutics 1.27% Reduce −17.9% 187,140 $26.70 $5M −40,766 −$1M
TELA - Tela Bio 1.11% New 1,441,029 $3.02 $4M +1,441,029 +$4M
PRQR - Proqr Therapeutics 1.06% Add +73.1% 1,567,561 $2.65 $4M +661,979 +$3M
KURA - Kura Oncology 0.99% Add +9.8% 448,368 $8.71 $4M +40,000 −$4M
RCUS - Arcus Biosciences 0.96% Reduce −1.0% 254,217 $14.89 $4M −2,500 −$140K
LKFT - Galapagos 0.91% Hold 130,175 $27.50 $4M
ALKS - Alkermes 0.88% Hold 120,700 $28.76 $3M
PODD - Insulet 0.82% Reduce −22.0% 12,400 $261.07 $3M −3,500 −$463K
CATBUSD - Astria Therapeutics 0.68% Add +17.9% 299,775 $8.94 $3M +45,610 −$118K
IMVT - Immunovant 0.68% Add +107.7% 107,996 $24.77 $3M +56,000 +$1M
ALLO - Allogene Therapeutics 0.67% Add +18.1% 1,240,118 $2.13 $3M +190,000 −$299K
VKTX - Viking Therapeutics 0.66% Reduce −48.6% 64,516 $40.24 $3M −61,100 −$5M
LXEO - Lexeo Therapeutics 0.66% Add +56.9% 393,083 $6.58 $3M +142,500 +$321K
ARAY - Accuray 0.62% Hold 1,222,358 $1.98 $2M
Keros Therapeutics 0.52% Add +76.7% 130,316 $15.83 $2M +56,562 −$2M
INGN - Inogen 0.49% Hold 208,790 $9.17 $2M
STOK - Stoke Therapeutics 0.48% Reduce −17.5% 171,097 $11.03 $2M −36,330 −$662K
BCAX - Bicara Therapeutics 0.47% New 105,500 $17.42 $2M +105,500 +$2M
BWAY - Brainsway 0.46% Reduce −23.1% 193,208 $9.43 $2M −58,138 −$500K
MLYS - Mineralys Therapeutics 0.46% Hold 146,500 $12.31 $2M
Immatics 0.44% Add +69.0% 245,000 $7.11 $2M +100,000 +$88K
ALEC - Alector 0.44% Hold 912,928 $1.89 $2M
IPSC - Century Therapeutics 0.44% Hold 1,704,232 $1.01 $2M
BCYC - Bicycle Therapeutics 0.43% Reduce −1.1% 120,799 $14.00 $2M −1,401 −$1M
Iteos Therapeutics 0.37% Add +16.6% 188,347 $7.68 $1M +26,763 −$203K
LRMR - Larimar Therapeutics 0.37% Reduce −24.9% 371,434 $3.87 $1M −122,840 −$2M
Regulus Therapeutics 0.35% Reduce −2.2% 875,200 $1.58 $1M −20,000 −$23K
AUTL - Autolus Therapeutics 0.35% Add +20.5% 586,667 $2.35 $1M +100,000 −$388K
Gossamer Bio 0.32% Reduce −0.7% 1,409,262 $0.9046 $1M −10,000 −$125K

Showing top 50 of 81 by value

Exits / last held

not current holdings · last reported size, unchanged · gone vs 2024 Q3

Stock % of portfolio Recent activity Shares Reported price* Value Share change $ change
Nyxoah S A 0.24% Exit 0 $9.55 $1M −108,108 −$1M
GRAL - Grail 0.16% Exit 0 $13.75 $671K −48,800 −$671K
Tourmaline Bio 0.12% Exit 0 $25.69 $491K −19,110 −$491K
VSTM - Verastem 0.09% Exit 0 $2.99 $382K −127,700 −$382K
Adaptimmune Therapeutics 0.08% Exit 0 $0.9500 $324K −341,064 −$324K
ANRO - Alto Neuroscience 0.07% Exit 0 $11.42 $306K −26,786 −$306K
Neuronetics 0.06% Exit 0 $0.7586 $238K −313,717 −$238K
Karyopharm Therapeutics 0.04% Exit 0 $0.8304 $160K −192,678 −$160K

* Reported price is value ÷ shares from the 13F as of period end — not a live market quote. Weight % is each long-equity position ÷ full 13F AUM, so rows may not sum to 100% when the filing includes options or other non-equity (excluded from this table). Share change and $ change are vs 2024 Q3. Click column headers to sort · click New / Hold / Add / Reduce to promote that move type to the top. Exit opens the last-held block below.

Filings history

20 periods · normalized AUM · open a period for holdings

Period Holdings AUM QoQ Form Filed Filing ID
2026 Q2 88 $524M +19.1% 13F-HR 8/14/2026 000138993326000006
2026 Q1 83 $440M +2.1% 13F-HR 5/15/2026 000138993326000004
2025 Q4 77 $431M +6.4% 13F-HR 2/17/2026 000138993326000002
2025 Q3 75 $405M +11.9% 13F-HR 11/14/2025 000138993325000008
2025 Q2 76 $362M +2.5% 13F-HR 8/14/2025 000138993225000011
2025 Q1 83 $353M −10.2% 13F-HR 5/15/2025 000138993325000002
2024 Q4 82 $393M −7.1% 13F-HR 2/14/2025 000138993225000004
2024 Q3 84 $423M +1.0% 13F-HR 11/14/2024 000138993224000020
2024 Q2 83 $419M −4.6% 13F-HR 8/14/2024 000138993224000016
2024 Q1 72 $439M +5.3% 13F-HR 5/15/2024 000138993224000012
2023 Q4 76 $417M +29.9% 13F-HR 2/14/2024 000138993224000004
2023 Q3 75 $321M −12.3% 13F-HR 11/14/2023 000138993223000010
2023 Q2 73 $366M +9.6% 13F-HR 8/14/2023 000138993323000008
2023 Q1 72 $334M −5.9% 13F-HR 5/15/2023 000138993323000006
2022 Q4 79 $355M −4.6% 13F-HR 2/14/2023 000138993323000002
2022 Q3 87 $372M +1.4% 13F-HR 11/14/2022 000138993322000010
2022 Q2 90 $367M −4.4% 13F-HR 8/15/2022 000138993322000008
2022 Q1 94 $384M −3.5% 13F-HR 5/16/2022 000138993322000006
2021 Q4 87 $398M +5.6% 13F-HR 2/14/2022 000138993322000002
2021 Q3 80 $377M 13F-HR 11/15/2021 000138993321000011

About

DAFNA Capital Management LLC

20 processed 13Fs on this site · 2021 Q3–2026 Q2

Entity
DAFNA Capital Management LLC
Notable person
Nathan Fischel
Location
Los Angeles, CA
All SEC filings
View on sec.gov