IONS Ionis Pharmaceuticals

• $1.1M bought by 1 insider
• $11.9M sold by 9 insiders outside a trading plan
• $102M sold by 18 insiders under 10b5-1 plans

1. Insider
   Trade
   Value
   Traded, filed
2. Michael R Hayden Director
   Buy
   $1.1M 20,000 shares at $52.94 +500% to stake
   Traded Jul 30–31 Filed Jul 31
   ↗
3. C Frank Bennett EVP, Chief Scientific Officer
   Planned sale
   $1.7M 20,536 shares at $84.95
   Traded Jul 7 Filed Jul 9
   ↗
4. Allene M. Diaz Director
   Planned sale
   $864K 10,111 shares at $85.42 73% of stake
   Traded Jul 7 Filed Jul 9
   ↗
5. Holly B. Kordasiewicz EVP, Chief Development Officer
   Planned sale
   $31K 362 shares at $84.30 1.6% of stake
   Traded Jul 7 Filed Jul 9
   ↗
6. Joseph Klein III Director
   Planned sale
   $910K 11,518 shares at $79.04 51% of stake
   Traded Jul 1 Filed Jul 6
   ↗
7. Joseph Baroldi EVP, Chief Business Officer
   Planned sale
   $452K 5,635 shares at $80.16 55% of stake
   Traded Jun 26 Filed Jun 30
   ↗
8. Patrick R. O'Neil EVP CLO & General Counsel
   Planned sale
   $246K 3,069 shares at $80.00 4.8% of stake
   Traded Jun 26 Filed Jun 30
   ↗
9. Eugene Schneider EVP, Chf Clinical Develop Ofcr
   Planned sale
   $2.1M 26,000 shares at $81.05 25% of stake
   Traded Jun 26 Filed Jun 30
   ↗
10. Brett P Monia CEO
    Planned sale
    $6.8M 85,637 shares at $79.70 26% of stake
    Traded Jun 24–26 Filed Jun 26
    ↗
11. Eric Swayze EVP Research
    Planned sale
    $839K 10,602 shares at $79.18 33% of stake
    Traded Jun 25 Filed Jun 26
    ↗
12. Holly B. Kordasiewicz EVP, Chief Development Officer
    Planned sale
    $4.5M 60,846 shares at $73.41 73% of stake
    Traded Jun 12 Filed Jun 16
    ↗
13. Spencer R Berthelsen Director
    Planned sale
    $588K 8,000 shares at $73.49 4.9% of stake
    Traded Jun 15 Filed Jun 16
    ↗
14. Spencer R Berthelsen Director
    Planned sale
    $605K 8,000 shares at $75.67 4.9% of stake
    Traded Jun 1 Filed Jun 3
    ↗
15. Brett P Monia CEO
    Planned sale
    $356K 4,536 shares at $78.49 1.8% of stake
    Traded May 13–14 Filed May 15
    ↗
16. Joseph Loscalzo Director
    Planned sale
    $5.8M 77,289 shares at $75.06 68% of stake
    Traded May 4 Filed May 6
    ↗

Also filed in the last 12 months, not counted as buying or selling: 95 option exercises, 18 sales to cover taxes, 11 other transactions, and 8 stock grants.