Opaleye Management Inc. activity
Every position James Silverman opened, added to, trimmed or closed between 2026 Q1 and 2026 Q2.
New
13
Add
15
Reduce
13
Exit
8
49 shown
| Ticker | Action | Δ weight | Detail | Period |
|---|---|---|---|---|
| IMMX | New | 0% to 2.2% | $24M | Q1→Q2 |
| GLUE | New | 0% to 1.6% | $18M | Q1→Q2 |
| REPL | New | 0% to 1.4% | $15M | Q1→Q2 |
| VSTM | New | 0% to 0.62% | $6.9M | Q1→Q2 |
| PHAT | New | 0% to 0.18% | $2M | Q1→Q2 |
| INBX | New | 0% to 0.17% | $1.9M | Q1→Q2 |
| COAG | New | 0% to 0.16% | $1.8M | Q1→Q2 |
| TRAX | New | 0% to 0.12% | $1.3M | Q1→Q2 |
| KTTA | New | 0% to 0.10% | $1.1M | Q1→Q2 |
| BHVN | New | 0% to 0.10% | $1.2M | Q1→Q2 |
| ADCT | New | 0% to 0.07% | $749K | Q1→Q2 |
| OKYO | New | 0% to 0.05% | $563K | Q1→Q2 |
| PTN | New | 0% to 0.02% | $221K | Q1→Q2 |
| CATX | Exit | 2.6% to 0% | $19M | Q1→Q2 |
| ASRT | Exit | 0.67% to 0% | $5.1M | Q1→Q2 |
| STRO | Exit | 0.63% to 0% | $4.8M | Q1→Q2 |
| TECX | Exit | 0.50% to 0% | $3.8M | Q1→Q2 |
| RIGL | Exit | 0.25% to 0% | $1.9M | Q1→Q2 |
| NXTC | Exit | 0.20% to 0% | $1.5M | Q1→Q2 |
| PLX | Exit | 0.10% to 0% | $738K | Q1→Q2 |
| LBRX | Exit | 0.05% to 0% | $358K | Q1→Q2 |
| IRON | Add | 3.6% to 5.7% | +103.1% sh | Q1→Q2 |
| MGTX | Add | 2.4% to 4.3% | +67.2% sh | Q1→Q2 |
| URGN | Add | 3.4% to 4.8% | +0.7% sh | Q1→Q2 |
| CBIO | Add | 3.2% to 2.2% | +0.5% sh | Q1→Q2 |
| CABA | Add | 0.49% to 1.1% | +180.0% sh | Q1→Q2 |
| EDIT | Add | 0.63% to 1.1% | +100.4% sh | Q1→Q2 |
| BBOT | Add | 0.06% to 0.48% | +1213.8% sh | Q1→Q2 |
| FDMT | Add | 0.14% to 0.40% | +197.8% sh | Q1→Q2 |
| LYEL | Add | 0.21% to 0.44% | +334.9% sh | Q1→Q2 |
| VYGR | Add | 0.58% to 0.38% | +3.0% sh | Q1→Q2 |
| RCKT | Add | 0.45% to 0.31% | +4.7% sh | Q1→Q2 |
| IRD | Add | 0.30% to 0.42% | +0.4% sh | Q1→Q2 |
| XOMA | Add | 1.2% to 1.3% | +12.8% sh | Q1→Q2 |
| ACOG | Add | 1.9% to 1.9% | +13.0% sh | Q1→Q2 |
| INTC | Add | 0.41% to 0.38% | +2.0% sh | Q1→Q2 |
| LQDA | Reduce | 11.7% to 17.7% | −3.8% sh | Q1→Q2 |
| HROW | Reduce | 13.2% to 9.2% | −15.3% sh | Q1→Q2 |
| RYTM | Reduce | 4.7% to 1.2% | −0.4% sh | Q1→Q2 |
| SNWV | Reduce | 2.2% to 0.28% | −68.8% sh | Q1→Q2 |
| ANNX | Reduce | 1.7% to 0.89% | −26.5% sh | Q1→Q2 |
| CGON | Reduce | 0.85% to 0.11% | −81.2% sh | Q1→Q2 |
| JBIO | Reduce | 0.79% to 0.29% | −66.1% sh | Q1→Q2 |
| DERM | Reduce | 0.59% to 0.22% | −63.5% sh | Q1→Q2 |
| FBIO | Reduce | 0.38% to 0.25% | −14.6% sh | Q1→Q2 |
| AVIR | Reduce | 0.23% to 0.10% | −27.2% sh | Q1→Q2 |
| BDSX | Reduce | 0.45% to 0.37% | −24.4% sh | Q1→Q2 |
| TRVI | Reduce | 0.54% to 0.52% | −10.2% sh | Q1→Q2 |
| QTTB | Reduce | 1.1% to 1.1% | −25.9% sh | Q1→Q2 |